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The FRAY subfamily of Ste20-like kinases in D. discoideum

DFray1 and Fray2 represent the FRAY-subfamily of Ste20-like kinases in D. discoideum (see sevkin for more information on Ste20 kinases).

In humans this family is represented by OSR (oxidative stress responsive kinase, a name that is a bit misleading as nobody showed a link between OSR and oxidative stress) and STLK3/SPAK. The fruit fly contains only the kinase Fray in this subfamily.

The Schleicher group is currently characterizing the phenotype of knockout mutants.

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